Cover Image

An overview of Osmotic Drug Delivery System: An update review

Hiren J. Patel, Vaishnavi P. Parikh

Abstract


The pharmaceutical industry has faced several marked challenges in order to bring new chemical entities (NCEs) into the market over the past few decades. Various novel drug delivery approaches have been used as a part of life cycle management from which Osmotic drug delivery systems look the most promising one. After discussing the history of osmotic pump development, this article looks at the principles, advantages and disadvantages of osmotic drug delivery systems. Then, the basic components of osmotic pump and factors affecting the design of oral osmotic drug delivery systems are discussed in detail. In the later part of the manuscript, various types of osmotic pumps available in the market and evaluation methods for osmotic drug delivery systems are discussed in detail.


Keywords


Osmotic Drug Delivery Systems, osmotic pump, semi-permeable membrane

Full Text:

PDF

References


Achilli, Andrea; T. Y. Cath; E. A. Marchand; and A. E. Childress. “The forward osmosis membrane bioreactor: a low fouling alternative to MBR processes.” Desalination 239.1-3, (2009): 10-21. Print.

Atef, Eman and A. A. Belmonte. “Formulation and In vitro and In vivo characterization of a phenytoin self-emulsifying drug delivery system (SEDDS).” European Journal of Pharmaceutical Sciences 35.4, (2008): 257-263. Print.

Cath, Tzahi.Y.; A. E. Childress; and M. Elimelech. “Forward osmosis: principles, applications, and recent developments.” Journal of Membrane Science 281.1-2, (2006): 70-87. Print.

Edavalath, Sudeesh; K. Shivanand; K. Prakasam; B. P. Rao; and G. Divakar. “Formulation development and optimization of controlled porosity osmotic pump tablets of diclofenac sodium.” International Journal of Pharmacy and Pharmaceutical Sciences 3.1, (2011): 80-87. Print.

Herbig, S. M.; J. Cardinal; R. W. Korsmeyer; and K. Smith. “Asymmetric-membrane tablet coatings for osmotic drug delivery.” Journal of Controlled Release 35.2-3, (1995): 127-136. Print.

Hiltrop, K. “Lyotropic liquid crystals, Liquid Crystals.” Springer, (1994) pp. 143-171. Print.

Hoffman, Allas. S. “The origins and evolution of “controlled” drug delivery systems.” Journal of Controlled Release 132.3, (2008): 153-163. Print.

Jain, Shashank; N. Patel; and S. Lin. “Solubility and dissolution enhancement strategies: current understanding and recent trends.” Drug development and industrial pharmacy 41.6, (2015a): 875-887. Print.

Jain, Shashank; N. Patel; P. Madan; and S. Lin. “Quality by design approach for formulation, evaluation and statistical optimization of diclofenac-loaded ethosomes via transdermal route.” Pharmaceutical development and technology 20.4, (2015b): 473-489. Print.

Jain, Shashank; N. Patel; P. Madan; and S. Lin. “Formulation and rheological evaluation of ethosome-loaded carbopol hydrogel for transdermal application.” Drug development and industrial pharmacy 42.8, (2016): 1315-1324. Print.

Jogani, Viral V.; P. J. Shah; P. Mishra; A. K. Mishra; and A. R. Misra. “Intranasal mucoadhesive microemulsion of tacrine to improve brain targeting.” Alzheimer Disease & Associated Disorders 22.2, (2008):116-124. Print.

Jogani, Viral V.; P. J. Shah; P. Mishra; A. K. Mishra; and A. R. Misra. “Nose‐to‐brain delivery of tacrine.” Journal of pharmacy and pharmacology 59.9, (2007): 1199-1205. Print.

Khanna, Satish C.. “Therapeutic system for sparingly soluble active ingredients.” Google Patents (1991). Publication number: US4992278 A

Kigasawa, Kaoru; K. Kajimoto; M. Watanabe; K. Kanamura; A. Saito; and K. Kogure. “In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol.” Biological and Pharmaceutical Bulletin 32.4, (2009): 684-687. Print.

Lee, K L.; R. Baker; and H. Lonsdale. “Membranes for power generation by pressure-retarded osmosis.” Journal of Membrane Science 8.2, (1981): 141-171. Print.

Liu, Dongfei; Y. Ge; Y. Tang; Y. Yuan; Q. Zhang; R. Li; and Q. Xu. “Solid lipid nanoparticles for transdermal delivery of diclofenac sodium: preparation, characterization and In vitro studies.” Journal of microencapsulation 27.8, (2010): 726-734. Print.

Liu, Dongfei; S. Jiang; H. Shen; S. Qin; J. Liu; Q. Zhang; R. Li; and Q. Xu. “Diclofenac sodium-loaded solid lipid nanoparticles prepared by emulsion/solvent evaporation method.” Journal of Nanoparticle Research 13.6, (2011): 2375-2386. Print.

Malaterre, Vincet; J. Ogorka; N. Loggia; and R. Gurny. “Approach to design push–pull osmotic pumps.” International journal of pharmaceutics 376.1-2, (2009): 56-62. Print.

Okimoto, Kazuto.; R. A. Rajewski; and V. J. Stella. “Release of testosterone from an osmotic pump tablet utilizing (SBE) 7m-β-cyclodextrin as both a solubilizing and an osmotic pump agent.” Journal of Controlled Release 58.1, (1999): 29-38. Print.

Padmanabhan, R. V.; J. Phipps; G. Lattin; and R. Sawchuk. “In vitro and In vivo evaluation of transdermal iontophoretic delivery of hydromorphone.” Journal of Controlled Release 11.1-3, (1990): 123-135. Print.

Patel, Niketkumar; S. Jain; and S. Lin. “Transdermal iontophoretic delivery of tacrine hydrochloride: Correlation between In vitro permeation and In vivo performance in rats.” International journal of pharmaceutics 513.1-2, (2016): 393-403.

Patel, Niketkumar; S. Jain; P. Madan; and S. Lin. “Influence of electronic and formulation variables on transdermal iontophoresis of tacrine hydrochloride.” Pharmaceutical development and technology 20.4, (2015): 442-457. Print.

Patel, Niketkumar; S. Jain; P. Madan; and S. Lin. “Application of design of experiments for formulation development and mechanistic evaluation of iontophoretic tacrine hydrochloride delivery.” Drug development and industrial pharmacy 42.11, (2016b): 1894-1902. Print.

Potluri, Raja Hemanth Kumar; S. Bandari; R. Jukanti; and P. R. Veerareddy. “Solubility enhancement and physicochemical characterization of carvedilol solid dispersion with Gelucire 50/13.” Archives of pharmacal research 34.1, (2011): 51-57. Print.

Santus, Giancarlo; and R. W. Baker. “Osmotic drug delivery: a review of the patent literature.” Journal of Controlled Release 35.1, (1995): 1-21. Print.

Shah, Mansi K., P. Madan; and S. Lin. “Preparation, In vitro evaluation and statistical optimization of carvedilol-loaded solid lipid nanoparticles for lymphatic absorption via oral administration.” Pharmaceutical development and technology 19.4, (2014): 475-485. Print.

Shah, Mansi K., P. Madan; and S. Lin. “Elucidation of intestinal absorption mechanism of carvedilol-loaded solid lipid nanoparticles using Caco-2 cell line as an in-vitro model.” Pharmaceutical development and technology 20.7, (2015): 877-885. Print.

Shamma, Rehab N.; and M. Basha. “Soluplus®: A novel polymeric solubilizer for optimization of Carvedilol solid dispersions: Formulation design and effect of method of preparation.” Powder technology 237, (2013): 406-414. Print.

Theeuwes, Felix. “Elementary osmotic pump.” Journal of pharmaceutical sciences 64.12, (1975.): 1987-1991. Print.

Theeuwes, Felix; D. Swanson; P. Wong; P. Bonsen; V. Place; K. Heimlich; and K. Kwan. “Elementary osmotic pump for indomethacin.” Journal of pharmaceutical sciences 72.3, (1983): 253-258. Print.

Theeuwes, Felix; and S. Yum. 1976. “Principles of the design and operation of generic osmotic pumps for the delivery of semisolid or liquid drug formulations.” Annals of biomedical engineering 4.4, (1976): 343-353. Print.

Thombre, Avinash G.; L. Appel; M. Chidlaw; P. Daugherity; F. Dumont; L. Evans; and S. Sutton. “Osmotic drug delivery using swellable-core technology.” Journal of Controlled Release 94.1, (2004): 75-89. Print.

Thombre, Avinash G. “Delivery device having encapsulated excipients.” Google Patents. (1997) Publication number: US 5697922 A.

Verma, R. K.; B. Mishra; and S. Garg. “Osmotically controlled oral drug delivery.” Drug development and industrial pharmacy 26.7, (2000): 695-708. Print.

Verma, R. K.; D. M. Krishna; and S. Garg. “Formulation aspects in the development of osmotically controlled oral drug delivery systems.” Journal of Controlled Release 79.1-3, (2002): 7-27. Print.

Wong, Patrick S.; F. Theeuwes; B. L. Barclay; and M. H. Dealey. “Osmotic dosage system for liquid drug delivery.” Google Patents. (1995) Publication number: US 5413572 A

Zentner, Gaylen M.; G. A. McClelland; and S. C. Sutton. “Controlled porosity solubility-and resin-modulated osmotic drug delivery systems for release of diltiazem hydrochloride.” Journal of Controlled Release 16.1-2, (1991): 237-243. Print.




DOI: http://dx.doi.org/10.21746/ijbio.2017.07.001

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 International Journal of Bioassays

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

International Journal of Bioassays is a member of the Publishers International Linking Association, Inc. (PILA), CROSSREF and CROSSMARK (USA). Digital Object Identifier (DOI) will be assigned to all its published content.